Etymology
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whammy (n.)

often double whammy, "hex, evil eye," 1932, of unknown origin, popularized 1941 in Al Capp's comic strip "Li'l Abner," where it was the specialty of Evil-Eye Fleegle.

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Definitions of whammy

whammy (n.)
a serious or devastating setback;
whammy (n.)
an evil spell;
he put the whammy on me
Synonyms: hex / jinx / curse
From wordnet.princeton.edu