Etymology
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upset (v.)

mid-15c., "to set up, fix," from up (adv.) + set (v.). Similar formation in Middle Dutch opsetten "set up, propose," German aufsetzen. Modern sense of "overturn, capsize" (1803) is that of obsolete overset. In reference to the stomach, from 1834. Meaning "to throw into mental discomposure" is from 1805. Related: Upsetting.

upset (n.)

early 15c., "insurrection," from upset (v.). Meaning "overturning of a vehicle or boat" is recorded from 1804.

upset (adj.)

early 14c., "erected," past-participle adjective from upset (v.). From 1805 as "distressed."

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Definitions of upset
1
upset (v.)
disturb the balance or stability of;
The hostile talks upset the peaceful relations between the two countries
upset (v.)
cause to lose one's composure;
Synonyms: discompose / untune / disconcert / discomfit
upset (v.)
move deeply;
This book upset me
Synonyms: disturb / trouble
upset (v.)
cause to overturn from an upright or normal position;
Synonyms: overturn / tip over / turn over / knock over / bowl over / tump over
upset (v.)
form metals with a swage;
Synonyms: swage
upset (v.)
defeat suddenly and unexpectedly;
The foreign team upset the local team
2
upset (n.)
an unhappy and worried mental state;
she didn't realize the upset she caused me
upset (n.)
the act of disturbing the mind or body;
his carelessness could have caused an ecological upset
Synonyms: derangement / overthrow
upset (n.)
a physical condition in which there is a disturbance of normal functioning;
everyone gets stomach upsets from time to time
Synonyms: disorder
upset (n.)
a tool used to thicken or spread metal (the end of a bar or a rivet etc.) by forging or hammering or swaging;
Synonyms: swage
upset (n.)
the act of upsetting something;
he was badly bruised by the upset of his sled at a high speed
Synonyms: overturn / turnover
upset (n.)
an improbable and unexpected victory;
the biggest upset since David beat Goliath
Synonyms: overturn
3
upset (adj.)
used of an unexpected defeat of a team favored to win;
the Bills' upset victory over the Houston Oilers
upset (adj.)
afflicted with or marked by anxious uneasiness or trouble or grief;
too upset to say anything
Synonyms: disquieted / distressed / disturbed / worried
upset (adj.)
thrown into a state of disarray or confusion;
with everything so upset
Synonyms: broken / confused / disordered
upset (adj.)
mildly physically distressed;
an upset stomach
upset (adj.)
having been turned so that the bottom is no longer the bottom;
the upset pitcher of milk
Synonyms: overturned / upturned
From wordnet.princeton.edu