unwell (adj.)

prefix of negation, Old English un-, from Proto-Germanic *un- (source also of Old Saxon, Old Frisian, Old High German, German un-, Gothic un-, Dutch on-), from PIE *n- (source of Sanskrit a-, an- "not," Greek a-, an-, Old Irish an-, Latin in-), combining form of PIE root *ne- "not." Often euphemistic (such as untruth for "lie").

The most prolific of English prefixes, freely and widely used in Old English, where it forms more than 1,000 compounds. It underwent a mass extinction in early Middle English, but emerged with renewed vigor 16c. to form compounds with native and imported words. It disputes with Latin-derived cognate in- (1) the right to form the negation of certain words (indigestable/undigestable, etc.), and though both might be deployed in cooperation to indicate shades of meaning (unfamous/infamous), typically they are not.

It also makes words from phrases (such as uncalled-for, c. 1600; undreamed-of, 1630s; uncome-at-able, 1690s; unputdownable, 1947, of a book; un-in-one-breath-utterable, Ben Jonson; etc., but the habit is not restricted to un-; such as put-up-able-with, 1812). As a prefix in telegramese to replace not and save the cost of a word, it is attested by 1936.

"in a satisfactory manner," Old English wel "abundantly, very, very much; indeed, to be sure; with good reason; nearly, for the most part," from Proto-Germanic *wel- (source also of Old Saxon wela, Old Norse vel, Old Frisian wel, Dutch wel, Old High German wela, German wohl, Gothic waila "well"), from PIE root *wel- (2) "to wish, will" (source also of Sanskrit prati varam "at will," Old Church Slavonic vole "well," Welsh gwell "better," Latin velle "to wish, will," Old English willan "to wish;" see will (v.)).

Also used in Old English as an interjection and an expression of surprise. The adjective was in Old English in the sense "in good fortune, happy," from the adverb; sense of "satisfactory" is from late 14c.; "agreeable to wish or desire" is from mid-15c.; "in good health, not ailing" is from 1550s. Well-to-do "prosperous" is recorded by 1794.