unmediated (adj.)

prefix of negation, Old English un-, from Proto-Germanic *un- (source also of Old Saxon, Old Frisian, Old High German, German un-, Gothic un-, Dutch on-), from PIE *n- (source of Sanskrit a-, an- "not," Greek a-, an-, Old Irish an-, Latin in-), combining form of PIE root *ne- "not." Often euphemistic (such as untruth for "lie").

The most prolific of English prefixes, freely and widely used in Old English, where it forms more than 1,000 compounds. It underwent a mass extinction in early Middle English, but emerged with renewed vigor 16c. to form compounds with native and imported words. It disputes with Latin-derived cognate in- (1) the right to form the negation of certain words (indigestable/undigestable, etc.), and though both might be deployed in cooperation to indicate shades of meaning (unfamous/infamous), typically they are not.

It also makes words from phrases (such as uncalled-for, c. 1600; undreamed-of, 1630s; uncome-at-able, 1690s; unputdownable, 1947, of a book; un-in-one-breath-utterable, Ben Jonson; etc., but the habit is not restricted to un-; such as put-up-able-with, 1812). As a prefix in telegramese to replace not and save the cost of a word, it is attested by 1936.

1540s, "divide in two equal parts" (a sense now obsolete), from Latin mediatus, past participle of mediare "to halve," later, "be in the middle," from Latin medius "middle" (from PIE root *medhyo- "middle"); from 1640s as "occupy a middle place or position." Meaning "act as a mediator, intervene for the purpose of reconciliation" is from 1610s; that of "settle by mediation, harmonize, reconcile" is from 1560s, perhaps back-formations from mediation or mediator. Related: Mediated; mediates; mediating.