Etymology
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unaffected (adj.)

1580s, "not influenced, untouched in mind or feeling," from un- (1) "not" + past participle of affect (v.). Meaning "not adopted or assumed, genuine" is recorded from 1590s; that of "not acted upon or altered (by something)" is first attested 1830. Related: Unaffectedly; unaffectedness.

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Definitions of unaffected

unaffected (adj.)
emotionally unmoved;
Synonyms: unmoved / untouched
unaffected (adj.)
unaware of or indifferent to;
Synonyms: insensible
unaffected (adj.)
undergoing no change when acted upon;
entirely unaffected by each other's writings
fibers remained apparently unaffected by the treatment
unaffected (adj.)
free of artificiality; sincere and genuine;
an unaffected grace
From wordnet.princeton.edu