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tribulation (n.)

"a state of affliction or oppression, suffering, distress," c. 1200, from Old French tribulacion (12c.), from Church Latin tribulationem (nominative tribulatio) "distress, trouble, affliction," noun of action from past-participle stem of tribulare "to oppress, afflict," a figurative use by Christian writers of Latin tribulare "to press," also possibly "to thresh out grain," from tribulum "threshing sledge," from stem of terere "to rub" (from PIE root *tere- (1) "to rub, turn") + -bulum, suffix forming names of tools.

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Definitions of tribulation from WordNet

tribulation (n.)
an annoying or frustrating or catastrophic event;
life is full of tribulations
Synonyms: trial / visitation
From wordnet.princeton.edu