Etymology
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trephine (n.)

an improved kind of trepan, 1620s, from French trephine, which is said to be from Latin tres fines "three ends," but perhaps rather an arbitrary diminutive of trepan. As a verb from 1804. Related: Trephining; trephination.

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Definitions of trephine
1
trephine (v.)
operate on with a trephine;
2
trephine (n.)
a surgical instrument used to remove sections of bone from the skull;
Synonyms: trepan
From wordnet.princeton.edu