Etymology
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Words related to transsexual

trans- 

word-forming element meaning "across, beyond, through, on the other side of, to go beyond," from Latin trans (prep.) "across, over, beyond," perhaps originally present participle of a verb *trare-, meaning "to cross," from PIE *tra-, variant of root *tere- (2) "cross over, pass through, overcome." In chemical use indicating "a compound in which two characteristic groups are situated on opposite sides of an axis of a molecule" [Flood].

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sexual (adj.)
1650s, "of or pertaining to the fact of being male or female," from Late Latin sexualis "relating to sex," from Latin sexus (see sex (n.)). Meaning "pertaining to copulation or generation" is from 1766; sexual intercourse attested by 1771; sexual orientation by 1967; sexual harassment by 1975. Sexual revolution attested by 1962. Sexual politics is from 1970. Related: Sexually.
transsexualism (n.)
"intense desire to change one's sexual status, including the anatomical structure," 1953, coined by U.S. physician Harry Benjamin (1885-1986) from trans- + sexual. Transsexuality is recorded from 1941, but was used at first to mean "homosexuality" or "bisexuality." In the current sense from 1955.
trannie (n.)
also tranny "transsexual person," 1983, from transsexual + -ie. In 1960s and '70s the word was used as a slang shortening of transistor radio and in car magazines for transmission.