Etymology
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transmutation (n.)

late 14c., from Old French transmutacion "transformation, change, metamorphosis" (12c.), from Late Latin transmutationem (nominative transmutatio) "a change, shift," noun of action from past-participle stem of Latin transmutare "change from one condition to another," from trans "across, beyond; thoroughly" (see trans-) + mutare "to change" (from PIE root *mei- (1) "to change, go, move"). A word from alchemy.

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Definitions of transmutation

transmutation (n.)
an act that changes the form or character or substance of something;
transmutation (n.)
a qualitative change;
Synonyms: transformation / shift
transmutation (n.)
(physics) the change of one chemical element into another (as by nuclear decay or radioactive bombardment);
the transmutation of base metals into gold proved to be impossible
From wordnet.princeton.edu