Etymology
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tranquilize (v.)

1620s, from tranquil + -ize. Related: Tranquilized; tranquilizing; tranquilization.

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Definitions of tranquilize

tranquilize (v.)
make calm or still;
Synonyms: calm / calm down / quiet / tranquillize / tranquillise / quieten / lull / still
tranquilize (v.)
cause to be calm or quiet as by administering a sedative to;
Synonyms: sedate / calm / tranquillize / tranquillise
From wordnet.princeton.edu