Etymology
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toothsome (adj.)

"pleasant to the taste," 1560s, from -some (1) + tooth in a figurative sense of "appetite, taste, liking" attested from late 14c. (compare sweet tooth, also figurative use of palate). The extended sense of "attractive" (1550s) is attested earlier. Related: Toothsomely; toothsomeness.

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Definitions of toothsome

toothsome (adj.)
acceptable to the taste or mind;
Synonyms: palatable
toothsome (adj.)
extremely pleasing to the sense of taste;
Synonyms: delectable / delicious / luscious / pleasant-tasting / scrumptious / yummy
toothsome (adj.)
having strong sexual appeal;
a toothsome blonde in a tight dress
Synonyms: juicy / luscious / red-hot / voluptuous / lush
From wordnet.princeton.edu