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tire (v.1)

"to weary," also "to become weary," Old English teorian (Kentish tiorian) "to fail, cease; become weary; make weary, exhaust," of uncertain origin; according to Watkins possibly from Proto-Germanic *teuzon, from a suffixed form of PIE root *deu- (1) "to lack, be wanting." Related: Tired; tiring.

tire (n.)

late 15c., "iron plates forming a rim of a carriage wheel," probably from tire "equipment, dress, covering" (c. 1300), a shortened form of attire (n.). The notion is of the tire as the dressing of the wheel. The original spelling was tyre, which had shifted to tire in 17c.-18c., but since early 19c. tyre has been revived in Great Britain and become standard there. Rubber ones, for bicycles (later automobiles) are from 1877. A tire-iron originally was one of the iron plates; as a device for separating a tire from a wheel, by 1909.

tire (v.2)

"furnish with a tire," 1899, from tire (n.).

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Definitions of tire from WordNet
1
tire (v.)
lose interest or become bored with something or somebody;
I'm so tired of your mother and her complaints about my food
Synonyms: pall / weary / fatigue / jade
tire (v.)
exhaust or get tired through overuse or great strain or stress;
Synonyms: wear upon / tire out / wear / weary / jade / wear out / outwear / wear down / fag out / fag / fatigue
tire (v.)
deplete;
Synonyms: run down / exhaust / play out / sap
tire (v.)
cause to be bored;
Synonyms: bore
2
tire (n.)
hoop that covers a wheel;
automobile tires are usually made of rubber and filled with compressed air
Synonyms: tyre
From wordnet.princeton.edu