Old English suð "southward, to the south, southern, in the south," from Proto-Germanic *sunthaz, perhaps literally "sun-side" (source also of Old Saxon, Old Frisian suth "southward, in the south," Middle Dutch suut, Dutch zuid, German Süden), and related to base of *sunnon "sun" (from PIE root *sawel- "the sun"). Old French sur, sud (French sud), Spanish sur, sud are loan-words from Germanic, perhaps from Old Norse suðr.
As an adjective from c. 1300; as a noun, "one of the four cardinal points," also "southern region of a country," both late 13c. The Southern states of the U.S. have been collectively called The South since 1779 (in early use this often referred only to Georgia and South Carolina). South country in Britain means the part below the Tweed, in England the part below the Wash, and in Scotland the part below the Forth. South Sea meant "the Mediterranean" (late 14c.) and "the English Channel" (early 15c.) before it came to mean (in plural) "the South Pacific Ocean" (1520s). The nautical coat called a sou'wester (1836) protects the wearer against severe weather, such as a gale out of the southwest.
superlative suffix of adjectives and adverbs, Middle English alteration (by influence of unrelated most) of Old English -mest, a double superlative, from -mo, -ma (cognate with Latin -mus; compare Old English forma "first," meduma "midmost") + superlative ending -est. Now generally mistaken as a suffixal form of most.