Etymology
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seven-year itch (n.)

1899, American English, some sort of skin condition (sometimes identified with poison ivy infection) that either lasts seven years or returns every seven years. Jocular use for "urge to stray from marital fidelity" is attested from 1952, as the title of the Broadway play (made into a film, 1955) by George Axelrod (1922-2003), in which the lead male character reads an article describing the high number of men have extra-marital affairs after seven years of marriage.

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Dictionary entries near seven-year itch

seventh

seventies

seventieth

seventy

seven-up

seven-year itch

sever

several

severally

severance

severe