1620s, "of symptoms, relating to signs of diseases," from Greek semeiotikos "significant," also "observant of signs," adjective form of semeiosis "indication," from semeioun "to signal, to interpret a sign," from semeion "a sign, mark, token," from sema "sign" (see semantic). Its use in psychology dates to 1923. Related: Semiotical (1580s).
in the names of sciences or disciplines (acoustics, aerobics, economics, etc.), a 16c. revival of the classical custom of using the neuter plural of adjectives with Greek -ikos "pertaining to" (see -ic) to mean "matters relevant to" and also as the titles of treatises about them. Subject matters that acquired their English names before c. 1500, however, tend to be singular in form (arithmetic, logic, magic, music, rhetoric). The grammatical number of words in -ics (mathematics is/mathematics are) is a confused question.
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Harper, D. (n.d.). Etymology of semiotics. Online Etymology Dictionary. Retrieved $(datetime), from https://www.etymonline.com/word/semiotics