word forming element indicating "oneself," also "automatic," from Old English use of self (pron.) in compounds, such as selfbana "suicide," selflice "self-love, pride, vanity, egotism," selfwill "free will." Middle English had self-witte "one's own knowledge and intelligence" (early 15c.).
OED counts 13 such compounds in Old English. Middle English Compendium lists four, counting the self-will group as a whole. It re-emerges as a living word-forming element mid-16c., "probably to a great extent by imitation or reminiscence of Greek compounds in (auto-)," and formed a great many words in the pamphlet disputes of the 17c.
mid-14c., "a consideration; a judgment," from Old French regard, regart, from regarder "take notice of," from re-, here perhaps an intensive prefix, + garder "look, heed," from a Germanic language (see guard (n.)).
Meanings "a look, appearance; respect, esteem, favor, kindly feeling which springs from a consideration of estimable qualities" all are recorded late 14c. Phrase in regard to is from mid-15c. (Chaucer uses at regard of).
<a href="https://www.etymonline.com/word/self-regard">Etymology of self-regard by etymonline</a>
Harper, D. (n.d.). Etymology of self-regard. Online Etymology Dictionary. Retrieved $(datetime), from https://www.etymonline.com/word/self-regard