scleroderma (n.)

before vowels scler-, word-forming element meaning "hard," from Latinized form of Greek sklēros "hard, harsh," which is related to skellein "to dry up, parch" (from PIE *skle-ro-, from root *skele- "to parch, wither").

Proto-Indo-European root meaning "to split, flay, peel," with derivatives referring to skin and leather.

It forms all or part of: derm; -derm; derma; dermal; dermato-; dermatology; echinoderm; epidermis; hypodermic; pachyderm; scleroderma; taxidermy; tart (adj.) "having a sharp taste;" tear (v.1) "pull apart;" tetter; turd.

It is the hypothetical source of/evidence for its existence is provided by: Sanskrit drnati "cleaves, bursts;" Greek derein "to flay;" Armenian terem "I flay;" Old Church Slavonic dera "to burst asunder;" Breton darn "piece;" Old English teran "to tear, lacerate."