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scleroderma (n.)

1866, from Modern Latin, from Greek skleros "hard" (see sclerosis) + derma "skin" (from PIE root *der- "to split, flay, peel," with derivatives referring to skin and leather). Related: Sclerodermatous; sclerodermatic.

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Definitions of scleroderma from WordNet
1
scleroderma (n.)
an autoimmune disease that affects the blood vessels and connective tissue; fibrous connective tissue is deposited in the skin;
Synonyms: dermatosclerosis
2
Scleroderma (n.)
genus of poisonous fungi having hard-skinned fruiting bodies: false truffles;
Synonyms: genus Scleroderma
From wordnet.princeton.edu