1580s, from French scientifique, from Medieval Latin scientificus "pertaining to science," from Latin scientia "knowledge" (see science) + -ficus "making, doing," from combining form of facere "to make, to do" (from PIE root *dhe- "to set, put"). Originally used to translate Greek epistemonikos "making knowledge" in Aristotle's "Ethics."
Sciential (mid-15c., "based on knowledge," from Latin scientialis) is the classical purists' choice for an adjective based on science. Scientic (1540s) and scient (late 15c.) also have been used. First record of scientific revolution is from 1803; scientific method is from 1854; scientific notation is from 1961. Related: Scientifical; scientifically.