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run-down (adj.)

1866, of persons, with reference to health, from verbal phrase, from run (v.) + down (adv.). From 1896 of places; 1894 of clocks. Earliest sense is "oppressed" (1680s).

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Definitions of run-down from WordNet

run-down (adj.)
worn and broken down by hard use;
a run-down neighborhood
Synonyms: creaky / decrepit / derelict / flea-bitten / woebegone
run-down (adj.)
having the spring unwound;
a run-down watch
From wordnet.princeton.edu