Etymology
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rubefacient (adj.)

"making red, causing redness," 1804, from Latin rubefacientem (nominative rubefaciens), present participle of rubefacere "to make red," from rubeus "red, reddish" (related to ruber, from PIE root *reudh- "red, ruddy") + facere "to make" (from PIE root *dhe- "to set, put"). As a noun, "substance producing redness in the skin," 1805.

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Definitions of rubefacient

rubefacient (n.)
a medicine for external application that produces redness of the skin;
From wordnet.princeton.edu