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region (n.)

c. 1300, regioun, "tract of land of a considerable but indefinite extent," also "a kingdom, country, nation; the people of a country," from Anglo-French regioun, Old French region "land, region, province" (12c.) and directly from Latin regionem (nominative regio) "a district, portion of a country, territory, district; a direction, line; boundary line, limit," noun of state from past-participle stem of regere "to direct, rule" (from PIE root *reg- "move in a straight line," with derivatives meaning "to direct in a straight line," thus "to lead, rule").

From late 14c. as "a part of the world," also "rural area around a city." Phrase in the region of "about" (of numbers, etc.) is attested from 1961.

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Definitions of region from WordNet

region (n.)
the extended spatial location of something;
the farming regions of France
regions of outer space
Synonyms: part
region (n.)
a part of an animal that has a special function or is supplied by a given artery or nerve;
in the abdominal region
Synonyms: area
region (n.)
a large indefinite location on the surface of the Earth;
penguins inhabit the polar regions
region (n.)
the approximate amount of something (usually used prepositionally as in `in the region of');
it was going to take in the region of two or three months to finish the job
Synonyms: neighborhood
region (n.)
a knowledge domain that you are interested in or are communicating about;
here we enter the region of opinion
Synonyms: realm
From wordnet.princeton.edu