1580s, "act of referring," from refer + -ance, or else from French référence, from Medieval Latin *referentia, from Latin referentem (nominative referens), present participle of referre. Meaning "direction to a book or passage" is recorded from 1610s. Meaning "testimonial" is from 1895. Reference book dates from 1808. Phrase in reference to is attested from 1590s.