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rankle (v.)

c. 1300, "to fester," from Old French rancler, earlier raoncler, draoncler "to suppurate, run," from draoncle "abscess, festering sore," from Medieval Latin dracunculus, literally "little dragon," diminutive of Latin draco "serpent, dragon" (see dragon). The notion is of an ulcer caused by a snake's bite. Meaning "cause to fester" is from c. 1400. Related: Rankled; rankling.

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Definitions of rankle from WordNet

rankle (v.)
gnaw into; make resentful or angry;
The injustice rankled her
Synonyms: eat into / fret / grate
From wordnet.princeton.edu