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quad

1820 as a shortening of quadrangle (n.) in the building-court sense (in this case "quadrangle of a college," Oxford student slang); also in old slang the quadrangle of a jail or prison, where prisoners take their exercise. By 1880 as short for the printer's quadrat (n.). By 1896 as "a quadricycle, a bicycle for four riders" (quadricycle is attested by 1879, quadruplet in this sense by 1893). As "one of four young at a single birth" by 1951 (in reference to armadillos), short for quadruplet; 1970 as a shortening of quadraphonic (adj.). Related: Quads.

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Definitions of quad from WordNet

quad (n.)
one of four children born at the same time from the same pregnancy;
Synonyms: quadruplet
quad (n.)
a muscle of the thigh that extends the leg;
Synonyms: quadriceps / quadriceps femoris / musculus quadriceps femoris
quad (n.)
(printing) a block of type without a raised letter; used for spacing between words or sentences;
Synonyms: space
quad (n.)
a rectangular area surrounded on all sides by buildings;
Synonyms: quadrangle
From wordnet.princeton.edu