pyrogen (n.)

before vowels pyr-, word-forming element form meaning "fire," from Greek pyr (genitive pyros) "fire, funeral fire," also symbolic of terrible things, rages, "rarely as an image of warmth and comfort" [Liddell & Scott], from PIE root *paewr- "fire." Pyriphlegethon, literally "fire-blazing," was one of the rivers of Hell.

word-forming element technically meaning "something produced," but mainly, in modern use, "thing that produces or causes," from French -gène (18c.), from Greek -genes "born of, produced by," which is from the same source as genos "birth," genea "race, family," from PIE root *gene- "give birth, beget," with derivatives referring to procreation and familial and tribal groups. First used in late 18th century French chemistry (see oxygen), it probably involves a misunderstanding of -genes, as though it meant "that which produces."

"the production of fire or heat," 1858; see pyro- + genesis. Pyrogenetic is attested from 1855 as "having the property of producing heat;" by 1838 in geology as "produced by heat."