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psychosis (n.)

1847, "mental affection or derangement," Modern Latin, from Greek psykhē "mind, life, soul" (see psyche) + -osis "abnormal condition." Greek psykhosis meant "a giving of life; animation; principle of life."

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Definitions of psychosis from WordNet

psychosis (n.)
any severe mental disorder in which contact with reality is lost or highly distorted;
From wordnet.princeton.edu