Etymology
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predisposition (n.)

"state of having a previous tendency or inclination in a particular direction, mental or physical susceptibility," 1620s, from pre- + disposition. Related: Predispositional.

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Definitions of predisposition

predisposition (n.)
susceptibility to a pathogen;
Synonyms: sensitivity
predisposition (n.)
an inclination beforehand to interpret statements in a particular way;
predisposition (n.)
a disposition in advance to react in a particular way;
From wordnet.princeton.edu