Etymology
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pother (n.)

1590s, "disturbance, commotion," a word of unknown origin. Meaning "mental trouble" is from 1640s; verb sense of "to fluster" is attested from 1690s. According to OED originally rhyming with other, brother; the pronunciation shift came in 19c. by influence of bother.

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Definitions of pother
1
pother (v.)
make upset or troubled;
pother (v.)
make a fuss; be agitated;
Synonyms: dither / flap
2
pother (n.)
an excited state of agitation;
Synonyms: dither / fuss / tizzy / flap
From wordnet.princeton.edu