Middle English -ik, -ick, word-forming element making adjectives, "having to do with, having the nature of, being, made of, caused by, similar to," from French -ique and directly from Latin -icus or from cognate Greek -ikos "in the manner of; pertaining to." From PIE adjective suffix *-(i)ko, which also yielded Slavic -isku, adjectival suffix indicating origin, the source of the -sky (Russian -skii) in many surnames. In chemistry, indicating a higher valence than names in -ous (first in benzoic, 1791).

In Middle English and after often spelled -ick, -ike, -ique. Variant forms in -ick (critick, ethick) were common in early Modern English and survived in English dictionaries into early 19c. This spelling was supported by Johnson but opposed by Webster, who prevailed.

word-forming element meaning "many, much, multi-, one or more," from Greek polys "much" (plural polloi), from PIE root *pele- (1) "to fill," with derivatives referring to multitudinousness or abundance. Equivalent to Latin multi-, it is properly used in compounds only with words of Greek origin. In chemical names, usually indicating a compound with a large number of atoms or molecules of the same kind (such as polymer).

1728, from Modern Latin syllabicus, from Greek syllabikos "of or pertaining to a syllable," from syllabē "a syllable" (see syllable). Related: Syllabical (1520s).