Etymology
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pisser (n.)

1901, slang, "the penis," also "the female pudendum." The slang meaning "extraordinary person or thing" is by 1943, now usually meaning an extraordinarily distasteful or unpleasant person or thing.

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Definitions of pisser

pisser (n.)
a person who urinates;
Synonyms: urinator
pisser (n.)
a very disagreeable difficulty;
From wordnet.princeton.edu