Etymology
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pissed (adj.)

1929, "drunk," past-participle adjective from piss (v.). From 1946 as "angry," from piss off.

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Definitions of pissed

pissed (adj.)
aroused to impatience or anger;
felt really pissed at her snootiness
Synonyms: annoyed / irritated / miffed / nettled / peeved / pissed off / riled / roiled / steamed / stung
pissed (adj.)
very drunk;
Synonyms: besotted / blind drunk / blotto / crocked / cockeyed / fuddled / loaded / pie-eyed / pixilated / plastered / slopped / sloshed / smashed / soaked / soused / sozzled / squiffy / stiff / tight / wet
From wordnet.princeton.edu