before vowels ophi-, word-forming element meaning "a snake, serpent," from Greek ophio-, combining form of ophis "serpent, a snake," probably from PIE *egwhi- (source also of Sanskrit ahi-, Avestan aži- "snake," and perhaps the first element of a Germanic word for "lizard," i.e. Old High German egi-dehsa). Hence ophiolatry "serpent-worship" (1862), and the 2c. sect of the Ophitæ, who revered the serpent as the symbol of divine wisdom.
word-forming element meaning "eating, feeding on," from Latin -phagus, from Greek -phagos "eater of," from phagein "to eat," literally "to have a share of food," from PIE root *bhag- "to share out, apportion; to get a share."
<a href="https://www.etymonline.com/word/ophiophagous">Etymology of ophiophagous by etymonline</a>
Harper, D. (n.d.). Etymology of ophiophagous. Online Etymology Dictionary. Retrieved $(datetime), from https://www.etymonline.com/word/ophiophagous