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noxious (adj.)
"unwholesome, harmful," c. 1500, noxius, from Latin noxius "hurtful, injurious," from noxa "injury, hurt, damage entailing liability" (related to nocere "to hurt," and to nex "slaughter"), from PIE *noks-, from root *nek- (1) "death." Related: Noxiously; noxiousness.