nihil (n.)

"nothing," 1833, from Latin nil, contraction of nihil, nihilum "nothing, not at all; in vain," from ne- "not" (from PIE root *ne- "not") + hilum "small thing, trifle," which is of unknown origin. The Latin phrase nil desperandum, used loosely for "never give up," is literally "nothing is to be despaired of," from the gerundive of desperare.