neurotic (adj.)

before vowels neur-, word-forming element meaning "pertaining to a nerve or nerves or the nervous system," from Greek neura "nerve" (Galen), originally "sinew, bowstring," also neuron "sinew, string (of a bow or musical instrument); cord; penis;" in plural "strength, vigor," from PIE *(s)neuro- "tendon, sinew" (see nerve (n.)). In Greek, puppets were neurospastos, literally "drawn by strings."

1776, "functional derangement arising from disorders of the nervous system (not caused by a lesion or injury)," coined by Scottish physician William Cullen (1710-1790) from Greek neuron "nerve" (see neuro-) + Modern Latin -osis "abnormal condition." Originally of epilepsy, hysteria, neuralgia, etc. Used in a general psychological sense from 1871, "change in the nerve cells of the brain resulting in symptoms of stress," but not radical loss of touch with reality (psychosis); clinical use in psychiatry dates from 1923.

"state or condition of being neurotic," 1894, from neurotic + -ism.