Etymology
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nettled (adj.)

"vexed, irritated," c. 1400, figurative adjectival use of past participle of nettle (v.).

Nettled. Teized, provoked, out of temper. He or she has pissed on a nettle; said of one who is pevish or out of temper. [Grose, "Dictionary of the Vulgar Tongue," 1785] 

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Definitions of nettled

nettled (adj.)
aroused to impatience or anger;
feeling nettled from the constant teasing
Synonyms: annoyed / irritated / miffed / peeved / pissed / pissed off / riled / roiled / steamed / stung
From wordnet.princeton.edu