Etymology
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monsignor (n.)

title conferred on some prelates and dignitaries of the papal court and household, 1640s, from Italian monsignore "my lord," formed on model of French monseigneur (see monseigneur) from equivalent elements in Italian.

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Definitions of monsignor

Monsignor (n.)
(Roman Catholic Church) an ecclesiastical title of honor bestowed on some priests;
From wordnet.princeton.edu