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mono

1959 as a shortening of monophonic in reference to recordings; earlier used among printers for "monotype machine" (c. 1925) and generally for monochrome (motorcar, etc.), 1940s. From 1964 as short for mononucleosis.

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Definitions of mono from WordNet

mono (adj.)
designating sound transmission or recording or reproduction over a single channel;
Synonyms: monophonic / single-channel
From wordnet.princeton.edu