microscopic (adj.)

"optical instrument which by means of a lens or lenses magnifies and renders visible minute objects or details of visible bodies," 1650s, from Modern Latin microscopium, literally "an instrument for viewing what is small;" see micro- + -scope. The dim southern constellation Microscopium was among those introduced by La Caille in 1752.

Middle English -ik, -ick, word-forming element making adjectives, "having to do with, having the nature of, being, made of, caused by, similar to," from French -ique and directly from Latin -icus or from cognate Greek -ikos "in the manner of; pertaining to." From PIE adjective suffix *-(i)ko, which also yielded Slavic -isku, adjectival suffix indicating origin, the source of the -sky (Russian -skii) in many surnames. In chemistry, indicating a higher valence than names in -ous (first in benzoic, 1791).

In Middle English and after often spelled -ick, -ike, -ique. Variant forms in -ick (critick, ethick) were common in early Modern English and survived in English dictionaries into early 19c. This spelling was supported by Johnson but opposed by Webster, who prevailed.

"visible to the naked eye," 1841, from macro- + ending from microscopic. Related: Macroscopical; macroscopically.