Etymology
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Words related to meso-

*medhyo- 
Proto-Indo-European root meaning "middle." Perhaps related to PIE root *me- (2) "to measure."

It forms all or part of: amid; intermediate; mean (adj.2) "occupying a middle or intermediate place;" medal; medial; median; mediate; medieval; mediocre; Mediterranean; medium; meridian; mesic; mesial; meso-; meson; Mesopotamia; Mesozoic; mezzanine; mezzo; mezzotint; mid (prep., adj.); middle; Midgard; midriff; midst; midwife; milieu; minge; mizzen; moiety; mullion.

It is the hypothetical source of/evidence for its existence is provided by: Sanskrit madhyah, Avestan madiya- "middle," Greek mesos, Latin medius "in the middle, between; from the middle," Gothic midjis, Old English midd "middle," Old Church Slavonic medzu "between," Armenian mej "middle."
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Mesoamerica (n.)

also Meso-America, cultural or economic region comprising central and southern Mexico and northern Central America, by 1948, from Spanish Mesoamérica (by 1943); see meso- "middle" + America. Related: Mesoamerican.

mesocracy (n.)
"government by the middle classes," 1858, from meso- "middle" + -cracy "rule or government by." Related: Mesocratic (1857).
mesoderm (n.)

"middle germinal layer of the three-layered embryo of a metazoic animal," 1858, from French mésoderme or German Mesoderm, literally "middle skin," coined by German physician Robert Remak (1815-1865) from meso- "middle" + Greek derma "skin" (see -derm). Related: Mesodermal; mesodermic.

mesolithic (adj.)

1866 in archaeology, "belonging to the middle Stone Age (in Europe, roughly 15,000 to 5,000 years before the present, between the paleolithic and the neolithic);  see meso- "middle" + lithic "consisting of stone." The word was used c. 1859 in a different sense in geology.

mesosphere (n.)

"region of the earth's atmosphere above the stratosphere and below the thermosphere," 1950, from meso- "middle" + second element in atmosphere.

mesothelioma (n.)

"malignant tumor of the mesothelium (usually that of the lungs)," typically caused by exposure to asbestos, by 1893, with -oma "morbid growth, tumor" + mesothelium (1886), which is from meso- "middle" + ending from epithelium.