Etymology
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mastery (n.)

c. 1200, mesterie, maistrie, "state or condition of being a master, control, dominance," also "superiority, ascendancy, the upper hand, victory in war or a contest;" from Old French maistrie (Modern French maîtrise), from maistre "master" (see master (n.)). Meaning "intellectual command" (of a topic, art, etc.), "expert skill" is from c. 1300.

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Definitions of mastery

mastery (n.)
great skillfulness and knowledge of some subject or activity;
Synonyms: command / control
mastery (n.)
power to dominate or defeat;
mastery of the seas
Synonyms: domination / supremacy
mastery (n.)
the act of mastering or subordinating someone;
Synonyms: subordination
From wordnet.princeton.edu