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marijuana (n.)

a preparation of Cannabis sativa for use as an intoxicant, generally by smoking, 1918, altered by influence of Spanish proper name Maria Juana "Mary Jane" from mariguan (1894), from Mexican Spanish marihuana, which is of uncertain origin. As the plant was not native to Mexico, a native source for the word seems unlikely.

Marijuana ... makes you sensitive. Courtesy has a great deal to do with being sensitive. Unfortunately marijuana makes you the kind of sensitive where you insist on everyone listening to the drum solo in Iron Butterfly's 'In-a-Gadda-Da-Vida' fifty or sixty times. [P.J. O'Rourke, "Modern Manners," 1983]

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Definitions of marijuana from WordNet

marijuana (n.)
a strong-smelling plant whose dried leaves can be smoked for a pleasant effect or pain reduction;
Synonyms: marihuana / ganja / Cannabis sativa
marijuana (n.)
the most commonly used illicit drug; considered a soft drug, it consists of the dried leaves of the hemp plant; smoked or chewed for euphoric effect;
Synonyms: cannabis / marihuana / ganja
From wordnet.princeton.edu