Etymology
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Words related to malignant

mal- 

word-forming element of Latin origin meaning "bad, badly, ill, poorly, wrong, wrongly," from French mal (adv.), from Old French mal (adj., adv.) "evil, ill, wrong, wrongly" (9c.), from Latin male (adv.) "badly," or malus (adj.) "bad, evil" (fem. mala, neuter malum), from Proto-Italic *malo-, from PIE *mol-o-, probably from PIE root *mel- (3) "false, bad, wrong."

Most Modern English words with this element are 19c. coinages. It generally implies imperfection or deficiency, but often it is simply negative (as in malfeasance, malcontent). It is equivalent to dys- and caco- of Greek origin and Germanic mis- (1).

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*gene- 

*genə-, also *gen-, Proto-Indo-European root meaning "give birth, beget," with derivatives referring to procreation and familial and tribal groups.

It forms all or part of: Antigone; autogenous; benign; cognate; congener; congenial; congenital; connate; cosmogony; cryogenic; degenerate; engender; engine; epigone; eugenics; -gen; gendarme; gender; gene; genealogy; general; generate; generation; generic; generous; genesis; -genesis; genial; -genic; genital; genitive; genius; genocide; genotype; genre; gens; gent; genteel; gentile; gentle; gentry; genuine; genus; -geny; germ; german (adj.) "of the same parents or grandparents;" germane; germinal; germinate; germination; gingerly; gonad; gono-; gonorrhea; heterogeneous; homogeneous; homogenize; homogenous; impregnate; indigenous; ingenious; ingenuous; innate; jaunty; kermes; kin; kindergarten; kindred; king; kind (n.) "class, sort, variety;" kind (adj.) "friendly, deliberately doing good to others;" Kriss Kringle; malign; miscegenation; nada; naive; nascent; natal; Natalie; nation; native; nature; nee; neonate; Noel; oncogene; ontogeny; photogenic; phylogeny; pregnant (adj.1) "with child;" primogenitor; primogeniture; progenitor; progeny; puisne; puny; renaissance; theogony; wunderkind.

It is the hypothetical source of/evidence for its existence is provided by: Sanskrit janati "begets, bears," janah "offspring, child, person," janman- "birth, origin," jatah "born;" Avestan zizanenti "they bear;" Greek gignesthai "to become, happen," genos "race, kind," gonos "birth, offspring, stock;" Latin gignere "to beget," gnasci "to be born," genus (genitive generis) "race, stock, kind; family, birth, descent, origin," genius "procreative divinity, inborn tutelary spirit, innate quality," ingenium "inborn character," possibly germen "shoot, bud, embryo, germ;" Lithuanian gentis "kinsmen;" Gothic kuni "race;" Old English cennan "beget, create," gecynd "kind, nature, race;" Old High German kind "child;" Old Irish ro-genar "I was born;" Welsh geni "to be born;" Armenian cnanim "I bear, I am born."

benignant (adj.)
"kind, gracious, favorable," 1739, from benign on model of its opposite, malignant. From 1790 as "exerting a good influence." Related: Benignantly; benignancy.
malignancy (n.)

c. 1600, "malignant nature;" 1650s, "state of extreme malevolence, bitter enmity," from malignant + abstract noun suffix -cy. Of diseases, growths, tumors, etc., "virulence, tendency to get worse," from 1680s. In English history, "adherence to the royal party in the time of Cromwell," 1640s, from malignants, a term applied to the royalists by their enemies.