Etymology
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Words related to malefic

mal- 

word-forming element of Latin origin meaning "bad, badly, ill, poorly, wrong, wrongly," from French mal (adv.), from Old French mal (adj., adv.) "evil, ill, wrong, wrongly" (9c.), from Latin male (adv.) "badly," or malus (adj.) "bad, evil" (fem. mala, neuter malum), from Proto-Italic *malo-, from PIE *mol-o-, probably from PIE root *mel- (3) "false, bad, wrong."

Most Modern English words with this element are 19c. coinages. It generally implies imperfection or deficiency, but often it is simply negative (as in malfeasance, malcontent). It is equivalent to dys- and caco- of Greek origin and Germanic mis- (1).

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*dhe- 

*dhē-, Proto-Indo-European root meaning "to set, put."

It forms all or part of: abdomen; abscond; affair; affect (v.1) "make a mental impression on;" affect (v.2) "make a pretense of;" affection; amplify; anathema; antithesis; apothecary; artifact; artifice; beatific; benefice; beneficence; beneficial; benefit; bibliothec; bodega; boutique; certify; chafe; chauffeur; comfit; condiment; confection; confetti; counterfeit; deed; deem; deface; defeasance; defeat; defect; deficient; difficulty; dignify; discomfit; do (v.); doom; -dom; duma; edifice; edify; efface; effect; efficacious; efficient; epithet; facade; face; facet; facial; -facient; facile; facilitate; facsimile; fact; faction (n.1) "political party;" -faction; factitious; factitive; factor; factory; factotum; faculty; fashion; feasible; feat; feature; feckless; fetish; -fic; fordo; forfeit; -fy; gratify; hacienda; hypothecate; hypothesis; incondite; indeed; infect; justify; malefactor; malfeasance; manufacture; metathesis; misfeasance; modify; mollify; multifarious; notify; nullify; office; officinal; omnifarious; orifice; parenthesis; perfect; petrify; pluperfect; pontifex; prefect; prima facie; proficient; profit; prosthesis; prothesis; purdah; putrefy; qualify; rarefy; recondite; rectify; refectory; sacrifice; salmagundi; samadhi; satisfy; sconce; suffice; sufficient; surface; surfeit; synthesis; tay; ticking (n.); theco-; thematic; theme; thesis; verify.

It is the hypothetical source of/evidence for its existence is provided by: Sanskrit dadhati "puts, places;" Avestan dadaiti "he puts;" Old Persian ada "he made;" Hittite dai- "to place;" Greek tithenai "to put, set, place;" Latin facere "to make, do; perform; bring about;" Lithuanian dėti "to put;" Polish dziać się "to be happening;" Russian delat' "to do;" Old High German tuon, German tun, Old English don "to do."

maleficence (n.)

1590s, "act of doing or producing evil," from French maleficence or directly from Latin maleficentia "an evildoing, mischievousness, injury," from maleficus "wicked" (see malefic). Sense of "malefic character" is by 1796.

*mel- (3)

Proto-Indo-European root meaning "false, bad, wrong." The exact sense of the root remains uncertain, "since it concerns a collection of largely isolated words in different IE branches" [de Vaan].

It forms all or part of: blame; blaspheme; blasphemous; blasphemy; ‌‌dismal; mal-; malady; malaise; malaria; malediction; malefactor; malefic; malevolence; malevolent; malice; malicious; malign; malison; malversation; mauvais.

It is the hypothetical source of/evidence for its existence is provided by: Avestan mairiia‑, "treacherous;" Greek meleos "idle; unhappy;" Latin male (adv.) "badly," malus (adj.) "bad, evil;" Old Irish mell "destruction;" Armenian mel "sin;" Lithuanian melas "lie," Latvian malds "mistake," possbily also Greek blasphemein "to slander."