mainstream (n.)

early 13c., "notably large, bulky, or strong" (a sense now obsolete), from Old English mægen- "power, strength, force," used in compounds (such as mægensibb "great love," mægenbyrðen "heavy burden;" see main (n.)), probably also in part from or influenced by cognate Old Norse megenn (adj.) "strong, powerful, mighty."

Sense of "chief, principal, prime" is from c. 1400. That of "principal or chief in size or extent" is from 1590s. Main chance "opportunity of enriching oneself" is by 1570s, from the game of hazard. Main course in the meal sense attested from 1829. Main man "favorite male friend; hero" is by 1967, African-American vernacular.

Old English stream "a course of water," from Proto-Germanic *strauma- (source also of Old Saxon strom, Old Norse straumr, Danish strøm, Swedish ström, Norwegian straum, Old Frisian stram, Dutch stroom, Old High German stroum, German Strom "current, river"), from PIE root *sreu- "to flow."

From early 12c. as "anything issuing from a source and flowing continuously." Meaning "current in the sea" (as in Gulf Stream) is recorded from late 14c., as is the sense of "steady current in a river." Stream of consciousness in lit crit first recorded 1930, originally in psychology (1855). Stream of thought is from 1890.