Etymology
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macule (n.)

"blemish, spot," late 15c., from Latin macula "a spot, stain" (see macula), perhaps via French macule. Compare macle.

updated on October 27, 2018

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Definitions of macule from WordNet

macule (n.)
a patch of skin that is discolored but not usually elevated; caused by various diseases;
Synonyms: macula
From wordnet.princeton.edu, not affiliated with etymonline.