plural maculae, "a spot, blotch," especially on the skin or eye, c. 1400, from Latin macula "spot, stain," used of various spots (sunspots, markings on minerals, etc.), from Proto-Italic *smalto-, which is of uncertain origin. The macula lutea of the eye, the yellow spot of the retina opposite the pupil (the position of the most distinct vision), is from 1848.
word-formation element meaning "pertaining to, of the nature of," from Latin -arem, -aris "of the kind of, belonging to," a secondary form (by dissimilation) of -alis, used after syllables with an -l- (such as insularis for *insulalis, stellaris for *stellalis).
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Harper, D. (n.d.). Etymology of macular. Online Etymology Dictionary. Retrieved $(datetime), from https://www.etymonline.com/word/macular