Etymology
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lousy (adj.)

mid-14c., lousi, "infested with lice," from louse (n.) + -y (2). Figurative use as a generic adjective of abuse dates from late 14c.; sense of "swarming with" (money, etc.) is American English slang from 1843. Related: Lousiness.

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Definitions of lousy

lousy (adj.)
very bad;
a lousy play
Synonyms: icky / crappy / rotten / shitty / stinking / stinky
lousy (adj.)
infested with lice;
burned their lousy clothes
lousy (adj.)
vile; despicable;
a dirty (or lousy) trick
Synonyms: dirty / filthy
From wordnet.princeton.edu