c. 1400, loscion, "liquid preparation for application to the skin," from Old French lotion (14c.), from Latin lotionem (nominative lotio) "a washing," noun of action from lotus (varied contraction of lavatus), popular form of lautus, past participle of lavere "to wash" (from PIE root *leue- "to wash").
1817, from lotion (n.). There is a nonce-use from 1768. Related: Lotioned; lotioning.
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